Creative Enzymes Analyses the Efficiency of Emodin for Drug Research
Emodin is a sort of subsidiary, existing in cassia seed, Caulis Polygoni Multiflori, Polygonum and other Chinese restorative herbs.
Shirley, United States – November 16, 2016 /MarketersMedia/ —
Emodin is a kind of derivative, existing in cassia seed, Caulis Polygoni Multiflori, Polygonum and other Chinese medicinal herbs. Below, Creative Enzymes will introduce a few kinds of efficiencies of emodin.
Pharmacological research
Anti-inflammation, anti-bacteria, anti-virus, anti-fungal, antigen-worm.
Nerve injury repair
Anti-tumor activity
Emodin has a significant inhibitory effect on many human and animal tumors, such as breast cancer, cervical cancer, pancreatic cancer, liver cancer, oral squamous cell carcinoma, leukemia and so on.
Renal protection, anti-renal interstitial fibrosis and diuretic effect
Liver protective effect
Emodin has the role of prevention and treatment of liver cancer and fatty liver, anti-liver fibrosis, inhibition of hepatitis B virus, and protection of impaired liver cells, etc.
Effect on gastrointestinal tract
Emodin has the function to treat diarrhea and ulcer caused by anti-helicobacter pylori, and can also protect rat intestinal membrane. Its mechanism may be the inhibition to produce tumor necrosis factor (TFN), release of a large number of NO, reduced generation of oxygen free radicals and aggregation&activation of neutrophil. Emodin can enhance intestinal peristalsis in mice, for its mechanism is to promote the secretion of motilin, reduce the content of somatostatin and inhibit ATP enzyme activity of small intestinal membrane.
Antioxidation
Emodin has antioxidation and free radical scavenging effect, and the prevention&treatment of atherosclerosis is related to lipid peroxidation. Emodin can significantly improve superoxide dismutase compounds (SOD) activity, decrease malondialdehyde (MD) content in serum, and increase glutathione peroxidase activity. As an effective antioxidant, it has obvious effect on the recovery of periodontal health.
Effect on cardiovascular system
The therapeutic effect on acute pancreatitis
The combined application of emodin and Astragalus can alleviate pancreatitis and lung injury, decrease the level of serum amylase, tissue necrosis factor and interleukin. The mechanism is to reduce expression of TLR4, and TLR4 plays an important role for acute pancreatic injury and inflammation.
Effect on the immune system
The biological method and spectrophotometric assays were used to determine the level of F-a, IL -1, IL-2 and C synthetized and secreted by macrophages. The results showed that emodin has a bidirectional regulation effect on the C secretion of NF.
Effect on bone metabolism
The role of emodin in bone metabolism is related to the following aspects. First of all, emodin can make the ovariectomized rats recover sex cycle quickly. Secondly, emodin has anti-superoxide anion radical activity and anti-aging effect.
In summary:
With the deep study of emodin, the extraction and separation, enzyme assay technology and clinical application prospects will gradually appear.
For more information, please visit http://www.creative-enzymes.com/
Contact Info:
Name: Lisa Clara
Organization: Creative Enzymes
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Phone: 5166698109
Release ID: 146721
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