Alfa Chemistry Catalysts Releases Chiral Oxazaborolidines for Asymmetric Synthesis
To facilitate relevant research, Alfa Chemistry Catalysts recently announces to provide a wide array of chiral oxazaborolidines, which belong to the category of asymmetric organocatalysts, for customers worldwide.
New York, United States – January 11, 2022 /MarketersMEDIA/ —
Asymmetric synthesis is a process that directly produces an optically active compound from symmetrically constituted molecules without requiring resolution of a racemic mixture. With its unique advantages, asymmetric synthesis has become an enabler for green chemistry. To facilitate relevant research, Alfa Chemistry Catalysts recently announces to provide a wide array of chiral oxazaborolidines, which belong to the category of asymmetric organocatalysts, for customers worldwide.
There are many approaches for asymmetric synthesis of active pharmaceutical ingredients (APIs), including chiral auxiliary based methodologies, biocatalysis, enzymatic transformations, the derivatization of compounds from the chiral pool, and many more. The use of asymmetric catalysis makes the whole synthesis process greener, taking into consideration factors like toxicity of reagents and waste generated.
“Asymmetric synthesis can be divided into three major categories: chiral pool synthesis, chiral auxiliaries, and asymmetric catalysis. Discovered in the 1980s, chiral oxazaborolidines are special catalysts that are widely used in a variety of Lewis acid-catalyzed organic chemical reactions. They plays an increasingly important role in the asymmetric reduction of ketone carbonyl, quinone imine, imine as well as Mukaiyama aldol reaction and enantioselective Diels-Alder addition,” says a spokesperson from Alfa Chemistry Catalysts.
Chiral oxazaborolidines bring better yield and enantioselectivity in synthesizing natural or non-natural products and biological active compounds. In the recent decade, study of chiral oxazaborolidines and their application are on the rise and more progress is achieved with concerted efforts from the science community.
With many years of hands-on laboratory practice in the field of chemical synthesis, the scientific team of Alfa Chemistry Catalysts knows what researchers truly need in their organic synthesis projects. To make chiral oxazaborolidines more easily obtainable, the company has released a new product line, offering a wide range of such catalysts for customers worldwide. Below are just some of them:
(S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (CAS 112022-81-8), (S)-4-Isopropyl-3-(1-naphthylmethyl)-2,5,5-triphenyl-1,3,2-oxazaborolidine (ca. 6% in Toluene, ca. 0.1mol/L) (CAS 850661-66-4), etc.
For more information about Alfa Chemistry Catalysts’ offering of chiral oxazaborolidines, please visit https://www.alfachemic.com/catalysts/products/chiral-oxazaborolidines.html or email us directly.
About Alfa Chemistry Catalysts
Ever since its establishment years ago, Alfa Chemistry Catalysts has been recognized as a trust-worthy supplier of varieties of catalysts in the pharmaceutical and biotechnology industries, offering chiral catalysts, ligands, metal catalysts, non-metal catalysts, organocatalysts, phase transfer catalysts, photocatalysts and many other catalysts to accelerate reactions and for other uses.
Contact Info:
Name: Tylor Keller
Email: Send Email
Organization: Alfa Chemistry
Address: New York, USA
Website: https://www.alfachemic.com/catalysts/
Source: MarketersMEDIA
Release ID: 89059575
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