Creative Diagnostics, a global leader in the supply of life science research products and services, has recently announced amine magnetic bead – a new product that brings the power, simplicity and convenience to researchers involved in cell biology, protein chemistry, flow cytometry, diagnostics development and many other fields.

Creative Diagnostics’ Amine Magnetic Beads are magnetic beads with an amine surface functional group. The magnetic beads consist of a single-crystal Fe3O4 sphere core and dextran coating layer. Through chemical modification of dextran, the primary amino group are joined to the magnetic beads through a short hydrophilic linker. The hydrophilic surface ensures the magnetic beads excellent dispersion ability and easy handling property in a wide variety of buffers.

The magnetic beads with surface-reactive amino groups allow immobilization of ligands such as proteins, peptides, carbohydrates or other target specific molecules. Immobilization of ligands can be through reductive amination of aldehyde or ketones without prior activation of the bead surface. Alternatively, carbodiimide cross-linkers can be used to couple ligands to the amines via their carboxyl groups. Finally, amine reactive heterobifunctional cross-linkers can be used to introduce other functional groups for coupling ligands.

“The visible, dense magnetic beads are easy to use, with simple, flexible protocols and elution conditions optimized, which can be used to covalently conjugate primary amine or carboxy-containing ligands,” Dr. Jessica Waldorf, chief scientific officer of R&D department of Creative Diagnostics, said. “Our easy-to-use, high-throughput tool helps customers address the challenges in early development for research success.”

Creative Diagnostics also offers a series of magnetic products for use in protein purification, proteomics, and genomics applications. High quality coating of magnetic silica beads with Steptavidin, Protein A, Protein G or other ligand specific molecules allows isolation of specific target molecules or cells out of large volumes or complex mixtures.

For more information about amine magnetic beads, please contact Creative Diagnostics at 1-631-624-4882 or email to info@creative-diagnostics.com.

Creative Diagnostics is a leading manufacturer and supplier of magnetic particles, antibody arrays, critical immunoassay kits and reagents. It is dedicated to providing the most comprehensive list of products and fit-for-purpose custom design services to academia as well as industrial researchers and assay developers all around the world.

Creative Diagnostics

Phone: 1-631-624-4882

Fax: 1-631-938-8221

Address: 45-1 Ramsey Road, Shirley, NY 11967, USA

Email: info@creative-diagnostics.com

Web: http://www.cd-bioparticles.com/